Description
Glutathione — Master Antioxidant Tripeptide for Redox Research (1500mg)
What is Glutathione?
Glutathione is a naturally occurring tripeptide composed of glutamic acid, cysteine and glycine (L-γ-glutamyl-L-cysteinyl-glycine). It is the most abundant intracellular antioxidant in the human body and is central to cellular redox homeostasis, detoxification and immune function research.
As a research compound, glutathione is studied for its role in neutralising reactive oxygen species (ROS), regenerating other antioxidants such as vitamins C and E, and serving as a cofactor for glutathione peroxidase and glutathione S-transferase enzymes. Its cysteine residue provides the reactive thiol group responsible for its antioxidant activity.
Mechanism of Research Interest
- ROS Scavenging: The thiol group of cysteine directly neutralises reactive oxygen and nitrogen species.
- Enzyme Cofactor: Serves as a substrate for glutathione peroxidases and glutathione S-transferases in redox and detoxification research.
- Redox Homeostasis: Maintains the intracellular glutathione/glutathione disulfide (GSH/GSSG) ratio used as a key marker of oxidative stress.
- Antioxidant Recycling: Participates in the regeneration of other antioxidants, including ascorbate and tocopherol.
Research Applications
- Oxidative stress and redox balance research
- Detoxification pathway studies
- Antioxidant defence mechanism research
- Cell culture supplement applications
Product Specifications
- Compound: Glutathione (L-γ-glutamyl-L-cysteinyl-glycine)
- Structure: Tripeptide
- Quantity: 1500mg
- Purity: ≥98% (HPLC verified)
- Form: Lyophilised powder
- Appearance: White powder
- Packaging: Individually sealed sterile vial
- Storage: Store at 2-8°C (refrigerated). Protect from light and moisture.
What’s Included
Note: This product does not contain BAC Water. Bacteriostatic water is available to purchase separately on the Cronopharm store.
Quality & Sourcing
All Cronopharm research products are sourced from reputable manufacturers and undergo quality verification. Each batch is tested for purity using HPLC analysis. We maintain strict cold-chain handling from warehouse to dispatch to ensure product integrity throughout the supply chain.
Key Research Benefits
- Master Antioxidant: Most abundant intracellular antioxidant for redox homeostasis research.
- Enzyme Cofactor: Substrate for glutathione peroxidase and S-transferase studies.
- Detoxification Research: Central to phase II detoxification pathway investigations.
- GSH/GSSG Assays: Supports oxidative stress biomarker measurements in cell models.
Reconstitution Guidelines
For experienced laboratory personnel only. This lyophilised powder must be reconstituted with bacteriostatic water prior to research use.
- Allow the vial to equilibrate to room temperature (15–25°C) before reconstitution.
- Wipe the rubber stopper with an alcohol swab and allow it to dry.
- Using a sterile syringe, add the required volume of Bacteriostatic Water by injecting slowly down the inner wall of the vial — do not aim the stream directly at the lyophilised cake.
- Gently swirl the vial until the powder is fully dissolved. Do not shake vigorously, as this can denature the peptide.
- Visually inspect the reconstituted solution — it should be clear and free of particulate matter.
- Store reconstituted solutions at 2–8°C and use within the timeframe defined in your research protocol. Discard any unused solution after the recommended period.
Important Notice
This product is for research and laboratory purposes only. It is not for human or veterinary consumption, not for medical use, and not for self-administration. This product has not been evaluated by the South African Health Products Regulatory Authority (SAHPRA) or any other regulatory body. The information provided is for educational and reference purposes only and should not be construed as medical advice. Researchers are responsible for ensuring compliance with all applicable laws and institutional guidelines governing the use of research products.
