Description

Cagritrutide Vial — Multi-Receptor Research Peptide for Comprehensive Metabolic Studies (36mg)

What is Cagritrutide?

Cagritrutide represents a next-generation approach to multi-receptor peptide research. It is a rationally designed peptide formulation that incorporates structural elements enabling activity at four distinct receptor systems: GLP-1 (glucagon-like peptide-1), GIP (glucose-dependent insulinotropic polypeptide), glucagon, and the amylin receptor system. This multi-pronged approach provides researchers with a uniquely comprehensive tool for investigating the integrated network of metabolic signalling pathways.

Unlike single or dual-receptor peptides, Cagritrutide’s multi-receptor profile allows simultaneous study of complementary and sometimes counter-regulatory signalling pathways. The glucagon receptor component — which distinguishes it from dual incretin approaches — activates signalling cascades associated with energy expenditure, while the amylin-like component adds a further dimension related to satiety signalling.

Receptor Targeting Profile

• GLP-1 Receptor (GLP-1R): Targets the classical incretin receptor pathway associated with appetite signalling, gastric function, and glucose-dependent hormone secretion. GLP-1R is a class B GPCR that signals primarily through cAMP/PKA pathways.
• GIP Receptor (GIPR): Engages the second major incretin receptor, complementing GLP-1 signalling with effects on nutrient-dependent hormone secretion and adipose tissue signalling.
• Glucagon Receptor (GCGR): Activates the glucagon signalling axis, which is typically associated with glycogenolysis, gluconeogenesis, and energy expenditure pathways. The glucagon component introduces study of catabolic signalling alongside anabolic incretin pathways.
• Amylin Receptor (AMYR): A calcitonin-family receptor that provides satiety signalling and gastric function modulation, mimicking the natural pancreatic hormone amylin (co-secreted with insulin).

Research Potential

The multi-receptor nature of Cagritrutide makes it particularly valuable for integrative metabolic research where the interplay between multiple hormonal signalling systems is of interest. Researchers can study how four distinct receptor pathways interact at the cellular and systemic level, potentially revealing network effects that simpler peptide tools cannot capture.

Product Description

Each vial contains 36mg of lyophilised Cagritrutide peptide powder. The peptide is supplied as a sterile freeze-dried preparation that can be reconstituted for laboratory use. The lyophilised form ensures stability during transport and storage.

Manufactured under controlled conditions with quality testing to verify purity. The powder presents as a white to off-white lyophilised cake or powder in a sealed glass vial.

Product Specifications

• Compound: Cagritrutide (Multi-Receptor Peptide Formulation: GLP-1/GIP/Glucagon/Amylin)
• Quantity: 36mg per vial
• Purity: ≥98% (HPLC verified)
• Form: Lyophilised sterile powder
• Packaging: Individually sealed, sterile glass vial
• Storage: 2-8°C (refrigerated). Protect from light and moisture.

What’s Included

Each order includes 1 × 3ml Bacteriostatic Water (BAC Water) for reconstituting the lyophilised powder. No additional reconstitution solution is required.

Key Research Benefits

• Four-Pathway Profile: GLP-1, GIP, glucagon and amylin receptor targeting in one research peptide.
• Comprehensive Metabolic Tool: Anabolic, catabolic and satiety signalling studied simultaneously.
• Receptor Interaction Studies: Investigates cross-talk across incretin, glucagon and amylin systems.
• Single-Vial Convenience: Multi-receptor research without compounding separate peptides.

Reconstitution Guidelines

For experienced laboratory personnel only. This lyophilised powder must be reconstituted with bacteriostatic water prior to research use.

• Allow the vial to equilibrate to room temperature (15–25°C) before reconstitution.
• Wipe the rubber stopper with an alcohol swab and allow it to dry.
• Using a sterile syringe, add the required volume of Bacteriostatic Water by injecting slowly down the inner wall of the vial — do not aim the stream directly at the lyophilised cake.
• Gently swirl the vial until the powder is fully dissolved. Do not shake vigorously, as this can denature the peptide.
• Visually inspect the reconstituted solution — it should be clear and free of particulate matter.
• Store reconstituted solutions at 2–8°C and use within the timeframe defined in your research protocol. Discard any unused solution after the recommended period.

Important Notice

This product is for research and laboratory purposes only. Not for human or veterinary consumption. Not for medical use. Not evaluated by SAHPRA or any other regulatory body. Information is for educational reference only. Researchers must comply with all applicable laws and institutional guidelines.