Description
AOD 9604 Vial — Modified hGH Fragment for Metabolic Signalling Research (5mg)
What is AOD 9604?
AOD 9604 is a synthetic 15-amino acid peptide corresponding to the lipolytic region of human growth hormone (hGH), specifically residues 177–191. It was engineered to isolate the metabolic activities associated with this region of the hGH molecule while removing the growth-promoting and glucose-regulating domains of the full hormone.
In research settings, AOD 9604 is studied as a standalone peptide fragment that interacts with hormone-sensitive signalling cascades involved in fat metabolism. Because it does not include the full growth hormone sequence, it is investigated as a tool for studying the region-specific functions of hGH without the broader endocrine effects of the intact hormone.
Mechanism of Research Interest
- Lipolytic Signalling: AOD 9604 is investigated for its capacity to modulate hormone-sensitive lipase activity and downstream cAMP-dependent pathways associated with triglyceride mobilisation in adipose tissue models.
- hGH Fragment Specificity: The peptide represents a defined structural region of hGH, allowing researchers to study structure-function relationships within the hormone without whole-molecule administration.
- Metabolic Cascade Studies: Research interest focuses on how the 177-191 fragment influences lipid oxidation and energy substrate utilisation at the cellular level.
Research Applications
- Lipolysis and fat metabolism research
- hGH fragment structure-function studies
- Adipocyte signalling pathway investigation
- Energy substrate utilisation assays
Product Specifications
- Compound: AOD 9604 (hGH fragment 177-191)
- Sequence Length: 15 amino acids
- Quantity: 5mg per vial
- Purity: ≥98% (HPLC verified)
- Form: Lyophilised (freeze-dried) sterile powder
- Appearance: White to off-white lyophilised cake
- Packaging: Individually sealed sterile glass vial
- Storage: Store at 2-8°C (refrigerated). Protect from light and moisture.
What’s Included
Note: This product does not contain BAC Water. Bacteriostatic water is available to purchase separately on the Cronopharm store.
Quality & Sourcing
All Cronopharm research products are sourced from reputable manufacturers and undergo quality verification. Each batch is tested for purity using HPLC analysis. We maintain strict cold-chain handling from warehouse to dispatch to ensure product integrity throughout the supply chain.
Key Research Benefits
- Targeted hGH Fragment: Residues 177-191 isolate the lipolytic region of hGH for focused metabolic research.
- Lipolysis Signalling: Investigated for hormone-sensitive lipase and cAMP pathway modulation.
- Fragment Specificity: Region-specific hGH study without whole-hormone endocrine effects.
- Metabolic Cascade Studies: Energy substrate utilisation and lipid oxidation research tool.
Reconstitution Guidelines
For experienced laboratory personnel only. This lyophilised powder must be reconstituted with bacteriostatic water prior to research use.
- Allow the vial to equilibrate to room temperature (15–25°C) before reconstitution.
- Wipe the rubber stopper with an alcohol swab and allow it to dry.
- Using a sterile syringe, add the required volume of Bacteriostatic Water by injecting slowly down the inner wall of the vial — do not aim the stream directly at the lyophilised cake.
- Gently swirl the vial until the powder is fully dissolved. Do not shake vigorously, as this can denature the peptide.
- Visually inspect the reconstituted solution — it should be clear and free of particulate matter.
- Store reconstituted solutions at 2–8°C and use within the timeframe defined in your research protocol. Discard any unused solution after the recommended period.
Important Notice
This product is for research and laboratory purposes only. It is not for human or veterinary consumption, not for medical use, and not for self-administration. This product has not been evaluated by the South African Health Products Regulatory Authority (SAHPRA) or any other regulatory body. The information provided is for educational and reference purposes only and should not be construed as medical advice. Researchers are responsible for ensuring compliance with all applicable laws and institutional guidelines governing the use of research products.
