Description

CJC-1295 no DAC + Ipamorelin Combo — GH Secretagogue Pair for Endocrine Research (5mg + 5mg)

What is this combo?

This combination pack pairs two growth hormone (GH) secretagogues that act through complementary mechanisms: CJC-1295 no DAC, a growth hormone releasing hormone (GHRH) analogue that stimulates GH release from pituitary somatotrophs, and Ipamorelin, a synthetic pentapeptide ghrelin mimetic that activates the ghrelin/growth hormone secretagogue receptor (GHSR).

In research settings, GHRH analogues and ghrelin mimetics are frequently studied in combination because their convergent but distinct signalling pathways allow investigation of additive or synergistic effects on the GH/IGF-1 axis. This pack provides both compounds for such protocol designs.

Mechanism of Research Interest

• CJC-1295 — GHRH Agonism: Activates pituitary GHRH receptors, stimulating growth hormone synthesis and release.
• Ipamorelin — GHSR Agonism: Activates the ghrelin receptor, providing a second, convergent stimulus to GH secretion pathways.
• Synergistic Pathway Research: Enables study of how dual secretagogue stimulation modulates GH pulse amplitude and IGF-1 output.
• Complementary Pharmacokinetics: The different half-lives of the two peptides allow research into temporal patterning of GH stimulation.

Research Applications

• Growth hormone axis signalling research
• Ghrelin receptor pharmacology studies
• Secretagogue combination protocols
• Endocrine pulse dynamics investigation

Product Specifications

• Compound 1: CJC-1295 no DAC (GHRH analogue, 29 aa)
• Compound 2: Ipamorelin (ghrelin mimetic, 5 aa)
• Quantity: 5mg + 5mg per pack
• Purity: ≥98% (HPLC verified)
• Form: Lyophilised (freeze-dried) sterile powders
• Packaging: Individually sealed sterile glass vials
• Storage: Store at 2-8°C (refrigerated). Protect from light and moisture.

What’s Included

Note: This product does not contain BAC Water. Bacteriostatic water is available to purchase separately on the Cronopharm store.

Quality & Sourcing

All Cronopharm research products are sourced from reputable manufacturers and undergo quality verification. Each batch is tested for purity using HPLC analysis. We maintain strict cold-chain handling from warehouse to dispatch to ensure product integrity throughout the supply chain.

Key Research Benefits

• Dual Secretagogue Pairing: GHRH analogue + ghrelin mimetic for complementary GH axis stimulation research.
• Synergy Studies: Enables investigation of additive or synergistic effects on GH/IGF-1 signalling.
• Pulse Dynamics Research: Contrasting half-lives support temporal patterning studies of GH release.
• Two Vials, One Protocol: Convenient pairing for combination protocol design.

Reconstitution Guidelines

For experienced laboratory personnel only. This lyophilised powder must be reconstituted with bacteriostatic water prior to research use.

• Allow the vial to equilibrate to room temperature (15–25°C) before reconstitution.
• Wipe the rubber stopper with an alcohol swab and allow it to dry.
• Using a sterile syringe, add the required volume of Bacteriostatic Water by injecting slowly down the inner wall of the vial — do not aim the stream directly at the lyophilised cake.
• Gently swirl the vial until the powder is fully dissolved. Do not shake vigorously, as this can denature the peptide.
• Visually inspect the reconstituted solution — it should be clear and free of particulate matter.
• Store reconstituted solutions at 2–8°C and use within the timeframe defined in your research protocol. Discard any unused solution after the recommended period.

Important Notice

This product is for research and laboratory purposes only. It is not for human or veterinary consumption, not for medical use, and not for self-administration. This product has not been evaluated by the South African Health Products Regulatory Authority (SAHPRA) or any other regulatory body. The information provided is for educational and reference purposes only and should not be construed as medical advice. Researchers are responsible for ensuring compliance with all applicable laws and institutional guidelines governing the use of research products.