Description

Cagrilintide Pre-Filled Pen — Amylin Analogue Research Formulation

Formulation Overview

The Cagrilintide Pre-Filled Pen delivers a long-acting amylin analogue in a convenient, sterile pre-filled format designed for research into the amylin signalling pathway. Amylin (also known as islet amyloid polypeptide or IAPP) is a naturally occurring 37-amino acid pancreatic hormone co-secreted with insulin by beta cells. Cagrilintide is a modified analogue with enhanced pharmacokinetic properties including prolonged half-life through fatty acid acylation.

The pre-filled pen format eliminates handling of lyophilised material, reducing protocol variables and simplifying administration in research models. No reconstitution or preparation is required.

Research Applications

• Amylin Signalling Research: Investigating the role of amylin receptor activation in appetite regulation, satiety signalling, and gastric function.
• Area Postrema Studies: Researching the circumventricular organ as the primary site of amylin-mediated central signalling.
• Pancreatic Hormone Axis: Exploring how amylin signalling interacts with insulin and incretin pathways in metabolic regulation.
• Gastric Function Research: Studying the effects of amylin receptor activation on gastric emptying rate and gastrointestinal motility.

Product Specifications

• Compound: Cagrilintide (Long-Acting Amylin Analogue)
• Receptor Target: Amylin Receptors (AMYR1, AMYR2, AMYR3)
• Format: Pre-filled, sterile, ready-to-use pen
• Presentation: Sterile solution
• Quality: Manufactured under controlled conditions with quality verification
• Storage: 2-8°C (refrigerated). Protect from light.

Key Research Benefits

• Amylin Receptor Signalling: Long-acting amylin analogue for research into AMYR1-3 receptor pharmacology and satiety signalling.
• Ready-to-Use Format: Sterile, pre-measured solution — no reconstitution or mixing required.
• Satiety Pathway Research: Area postrema and brainstem signalling studies relevant to appetite regulation research.
• Complementary Axis Studies: Amylin signalling investigated alongside insulin and incretin pathways in metabolic research.

How to Use (Research Application)

For experienced laboratory personnel only. This product is a sterile, ready-to-use pre-filled pen for research applications — no reconstitution required.

• Remove the pen from refrigeration and allow it to reach room temperature before use.
• Select the required dose on the pen dial as defined in your research protocol.
• Use sterile technique and attach a fresh needle for each administration.
• Rotate administration sites according to your research protocol.
• Store the pen at 2–8°C when not in use. Do not freeze. Dispose of used needles safely.

Important Notice

This product is for research and laboratory purposes only. Not for human or veterinary consumption. Not for medical use. Not evaluated by SAHPRA. For experienced researchers. Information is for educational reference. Researchers must comply with all applicable regulations.